Lee B, Baek JI, Min H, Bae SH, Moon K, Kim MA, Kim YR, Fogelgren B, Lipschutz JH, Lee KY, Bok J*, and Kim UK* (2018). Exocyst Complex Member EXOC5 Is Required for Survival of Hair Cells and Spiral Ganglion Neurons and Maintenance of Hearing. Mol Neurobiol. In Press (*corresponding authors) PubMed

Hashimoto H, Jiang W, Yoshimura T, Moon KH, Bok J, and Ikenaka K (2017). Strong sonic hedgehog signaling in the mouse ventral spinal cord is not required for oligodendrocyte precursor cell (OPC) generation but is necessary for correct timing of its generation. Neurochem Int. In Press. PubMed

Lee S^, Shin JO^, Sagong B, Kim UK*, and Bok J* (2017) Spatiotemporal expression patterns of clusterin in the mouse inner ear. Cell Tissue Res 370(1): 89-97 (^equal contribution, *corresponding authors) PubMed

Shin JO^, Ankamreddy H^, Jakka NM, Lee S, Kim UK, and Bok J* (2017) Temporal and spatial expression patterns of Hedgehog receptors in the developing inner and middle ear. Int J Dev Biol 61(8-9): 557-563. (^equal contribution) PubMed

Woo YM, Kim DY, Koo NJ, Kim YM, Lee S, Ko JY, Shin Y, Kim BH, Mun H, Choi S, Lee EJ, Shin JO, Park EY, Bok J, and Park JH (2017) Profiling of miRNAs and target genes related to cystogenesis in ADPKD mouse models. Sci Rep 7(1): 14151 PubMed

Lee JM, Kim JY, Bok J, Kim KS, Choi JY, and Kim SH (2017) Identification of evidence for autoimmune pathology of bilateral sudden sensorineural hearing loss using proteomic analysis. Clin Immunol 183: 24-35 PubMed

Ryu N, Lee S, Park HJ, Lee B, Kwon TJ, Bok J, Park CI, Lee KY, Baek JI, and Kim UK (2017) Identification of a novel splicing mutation within SLC17A8 in a Korean family with hearing loss by whole-exome sequencing. Gene 627: 233-238 PubMed

Kim JW^, Lee JH^, Ma JH^, Chung E, Choi H, Bok J, and Cheon J (2016) Magnetic Force Nanoprobe for Direct Observation of Audio Frequency Tonotopy of Hair Cells. Nano Lett 16(6): 3885-3891 (^eqaul contribution) PubMed

Sagong B, Baek J-I, Bok J, Lee K-Y, and Kim U-K (2016) Identification of a nonsense mutation in the STRC gene in a Korean family with moderate hearing loss. Int J Pediatr Otorhinolaryngol 80(1): 78-81 PubMed

Son EJ^,  Ma JH^,  Ankamreddy H,  Shin JO,  Choi JY,  Wu DK, and Bok J* (2015) Conserved role of Sonic Hedgehog in tonotopic organization of the avian basilar papilla and mammalian cochlea. Proc Natl Acad Sci U.S.A. 112(12): 3746-51 (^eqaul contribution) PubMed

Oh SK^, Shin JO^, Baek JI^, Lee J, Bae JW, Ankamerddy H, Kim MJ, Huh TL, Ryoo ZY, Kim UK, Bok J* and Lee KY* (2015) Pannexin 3 is required for normal progression of skeletal development in vertebrates. FASEB J 29:4473-84 (^equal contribution, *corresponding authors) PubMed

Moon J, Song J, Shin JO, Lee H, Kim HK, Eggenschwiller JT, Bok J*, and Ko HW* (2014) Intestinal cell kinase, a protein associated with endocrine-cerebro-osteodysplasia syndrome, is a key regulator of cilia length and Hedgehog signaling. Proc Natl Acad Sci U.S.A. 111(23): 8541-46 (*corresponding authors) PubMed

Kim HK, Ankamerddy H, Lee DJ, Kong KA, Ko HW, Kim MH, and Bok J* (2014) Pax3 function is required specifically for inner ear structures with melanogenic fates. Biochem Biophys Res Comm 445(3):608-14 PubMed

Kwon TJ, Cho HJ, Kim UK, Lee E, Oh SK, Bok J, Bae YC, Yi JK, Lee JW, Ryoo ZY, Lee SH, Lee KY, Kim HY (2014) Methionine sulfoxide reductase B3 deficiency causes hearing loss due to stereocilia degeneration and apoptotic cell death in cochlear hair cells. Hum Mol Genet15;23(6):1591-601 PubMed

Kim BG, Kim JY, Kim HN, Bok J, Namkung W, Choi JY and Kim SH (2014) Developmental Changes of ENaC Expression and Function in the Inner Ear of Pendrin Knock-Out Mice as a Perspective on the Development of Endolymphatic Hydrops. PLoS ONE 9(4): e95730 PubMed

Kwon TJ, Oh SK, Park HJ, Sato O, Venselaar H, Choi SY, Kim S, Lee KY, Bok J, Lee SH, Vriend G, Ikebe M, Kim UK and Choi JY (2014) The effect of novel mutations on the structure and enzymatic activity of unconventional myosins associated with autosomal dominant non-syndromic hearing loss. Open Biol 4(7): 140107 PubMed

Lee HJ, Jung J, Shin JW, Song MH, Kim SH, Lee JH, Lee KA, Shin S, Kim UK, Bok J, Lee KY, Choi JY and Park HJ (2014) Correlation between genotype and phenotype in patients with bi-allelic SLC26A4 mutations. Clin Genet 86(3): 270-275 PubMed

Bok J*, Zenczak C, Hwang CH and Wu DK* (2013) Auditory ganglion source of Sonic hedgehog regulates timing of cell cycle exit and differentiation of mammalian cochlear hair cells. Proc Natl Acad Sci U.S.A.110 (34): 13869-13874 (*corresponding authors) PubMed

Wu L, Sagong B, Choi JY, KimUK, and Bok J* (2013) A systematic survey of carbonic anhydrase mRNA expression during mammalian inner ear development. Developmental Dynamics 242(3): 269-280 PubMed

Cho HJ, Song MH, Choi SY, Kim J, Lee J, Kim UK, Bok J*, and Choi JY* (2013) Genetic analysis of the CHD7 gene in Korean patients with CHARGE syndrome. Gene 517(2): 164-168 (*corresponding authors) PubMed

Bok J* (2013) Role of Hedgehog and Wnt signaling in mammalian inner ear formation. In D.A. Frenz (Ed.) Molecular Signaling of Mammalian Inner Ear Development (pp. 97-108). Nova Science Publishers, Inc. (A book chapter)

Choi BY, Kim DH, Chang M, Kim EH, Kim AR, Seok J, Chang SO, Chung T, Bok J, Kim D, Oh SH, and Park WY (2013) Destabilization and Mislocalization of POU3F4 by C-Terminal Frameshift Truncation and Extension Mutation. Human mutation 34(2): 309-316 PubMed

Kim HJ, Woo HM, Ryu J, Bok J, Kim JW, Choi SB, Park MH, Park HY and Koo SK (2013) Conditional deletion of pten leads to defects in nerve innervation and neuronal survival in inner ear development. PLoS ONE 8(2): e55609PubMed

Son EJ, Wu L, Yoon HJ, Kim S, Choi JY, Bok J* (2012) Developmental gene expression profiling along the tonotopic axis of the mouse cochlea. PLoS ONE 7(7): e40735 PubMed

Song MH, Lee KY, Choi JY, Bok J*, and Kim UK* (2012) Nonsyndromic X-linked hearing loss. Frontiers in Bioscience 4: 924-933. (*corresponding authors) PubMed

Bok J*, Raft S, Kong KA, Koo SK, Dräger UC, and Wu DK* (2011) Transient retinoic acid signaling confers anterior-posterior polarity to the inner ear. Proc Natl Acad Sci U.S.A. 108(1): 161-166. (*corresponding authors) PubMed

Song MH, Choi SY, Wu L, Oh SK, Lee HK, Lee DJ, Shim DB, Choi JY, Kim UK, and Bok J* (2011) Pou3f4 deficiency causes defects in otic fibrocytes and stria vascularis by different mechanisms. Biochem Biophys Res Comm 404(1): 528-533 PubMed

Yoon HJ, Lee DJ, Kim MH, and Bok J* (2011) Identification of genes concordantly expressed with Atoh1 during inner ear development. Anatomy and Cell Biology 44(1): 69-78 PubMed

Choi SY, Lee KY, Kim HJ, Kim HK, Chang Q, Park HJ, Jeon CJ, Lin X, Bok J, Kim UK (2011) Functional Evaluation of GJB2 Variants in Nonsyndromic Hearing Loss. Molecular Medicine 17(5-6): 550-556 PubMed

Kim SH, Kim U-K, Lee W-S, Bok J, Song J-W, Seong JK, Choi JY (2011) Albumin-Like Protein is the Major Protein Constituent of Luminal Fluid in the Human Endolymphatic Sac. PLoS ONE 6(6): e21656 PubMed

Song, MH, Cho HJ, Lee HK, Kwon TJ, Lee WS, Oh S, Bok J, Choi JY and Kim UK (2011). CHD7 Mutational Analysis and Clinical Considerations for Auditory Rehabilitation in Deaf Patients with CHARGE Syndrome. PLoS ONE 6(9): e24511 PubMed

Song MH, Lee HK, Choi JY, Bok J*, and Kim UK* (2010) Clinical evaluation of DFN3 patients with deletions in the POU3F4 locus and detection of carrier female by MLPA. Clinical Genetics 78(6): 524-532. (*corresponding authors) PubMed

Bok J* (2010) Building the mammalian cochlea - an overview. Genes & Genomics 32(1): 1-7. SpringerLink

Liang JK, Bok J*, and Wu DK* (2010) Distinct contributions from the hindbrain and mesenchyme to inner ear morphogenesis. Developmental Biology337(2): 324-334. (*corresponding authors) PubMed

Min H, Lee JY, Bok J, Chung HJ, and Kim MH (2010) Proliferating cell nuclear antigen (Pcna) as a direct downstream target gene of Hoxc8. Biochem Biophys Res Comm 392(4): 543-547 PubMed

Kang M*, Bok J*, Deocaris CC, Park HW and Kim MH (2010) Hoxc8 represses BMP-induced expression of Smad6. Molecules & Cells 29(1): 29-33. (*equal contribution) PubMed

Lee HK, Song MH, Kang M, Lee JT, Kong KA, Choi SJ, Lee KY, Venselaar H, Vriend G, Lee WS, Park HJ, Kwon TK, Bok J* and Kim UK* (2009) Clinical and molecular characterizations of novel POU3F4 mutations reveal that DFN3 is due to null function of POU3F4 protein. Physiological Genomics 39: 195-201. (*corresponding authors) PubMed

Choi SY, Park HJ, Lee KY, Dinh EH, Chang Q, Ahmad S, Lee SH, Bok J, Lin X and Kim UK (2009) Different functional consequences of two missense mutations in the GJB2 gene associated with non-syndromic hearing loss. Human Mutation 30(7): E716-E727 PubMed

Kong KA, Gadi J, Park HW, Bok J*, and Kim MH* (2008) The third helix of the murine Hoxc8 homeodomain facilitates protein transduction in mammalian cells. Biochem Biophys Res Commun 377(1): 161-164. (*corresponding authors) PubMed

Bok J, Dolson DK, Hill P, Ruther U, Epstein DJ and Wu DK (2007) Opposing gradients of Gli repressor and activators mediate Shh signaling alongthe dorsoventral axis of the inner ear. Development 134(9): 1713-1722. (Featured in "IN THIS ISSUE" of the Journal) PubMed

Bok J, Chang W and Wu DK (2007) Pattering and morphogenesis of the vertebrate inner ear. International Journal of Developmental Biology 51: 521-533. (Cover for the issue) PubMed

Bok J, Brunet LJ, Howard O, Burton Q and Wu DK (2007) Role of hindbrain in inner ear morphogenesis: Analysis of Noggin knockoutmice. Developmental Biology 311(1): 69-78 PubMed

Bok J, Wang Q, Huang J, Green SH (2007) CaMKII and CaMKIV mediate distinct prosurvival signaling pathways in response to depolarization in neurons. Mol Cell Neurosci 36(1):13-26 PubMed

Bok J, Bronner-Fraser M and Wu DK (2005) Role of the hindbrain in dorsoventral but not anteroposterior axial specification of the inner ear. Development 132(9): 2115-2124. (Featured in "IN THIS ISSUE" of the Journal) PubMed

Bok J, Zha XM, Cho YS and Green SH (2003) An extranuclear locus of cAMP-dependent protein kinase action is necessary and sufficient for promotion of spiral ganglion neuronal survival by cAMP. Journal of Neuroscience 23(3): 777-787. (Featured in "THIS WEEK IN THE JOURNAL") PubMed

Hansen MR, Bok J, Devaiah AK, Zha XM and Green SH (2003) Ca2+/calmodulin-dependent protein kinases II and IV both promote survival but differ in their effects on axon growth in spiral ganglion neurons. Journal of Neuroscience Research 72(2): 169-184. PubMed

Hansen MR, Zha XM, Bok J, and Green SH (2001) Multiple distinct signal pathways, including an autocrine neurotrophic mechanism, contribute to the survival-promoting effect of depolarization on spiral ganglion neurons in vitro. Journal of Neuroscience 21(7): 2256-2267. PubMed